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Betting on Designer Genes. Jeff Wheelwright.

by Wheelwright, Jeff; Eckhart, Walter; SIRS Publishing, Inc.
Material type: materialTypeLabelBookSeries: SIRS Enduring Issues 2002Article 21Science. Publisher: Wheelwright/Jeff, 2001; World Link, 2001ISSN: 1522-3264;.Subject(s): University of California | Gene therapy -- Research | Genetic vectors | Heart -- Genetic aspects. -- Diseases | Human experimentation in medicine | Medical ethics | Medical genetics | VirusesDDC classification: 050 Summary: BETTING ON DESIGNER GENES -- "Scientists dream of giving people new genes that will stop a disease or fix a problem. It is harder than anyone thought." (SMITHSONIAN) This article reviews the development of gene-therapy techniques and examines problems that have stymied further progress.Summary: NEW PAIRS OF GENES -- "Although progress in gene therapy has been slow, it seems certain to be ultimately successful. The accumulated knowledge from basic research is providing multiple novel approaches to overcome problems and limitations. Progress in sequencing the human genome is providing a wealth of new material and identifying more diseases that have a genetic basis. For now the focus is on improving the vectors, the expression systems and the ability to target particular cells. The recent encouraging result with immune deficiency and haemophilia augur success. Yet as we anticipate further progress, it would be wise to ponder the deeper meanings of our ability to manipulate our genetic heritage, and what it portends for our future." (WORLD LINK) This article examines the techniques, applications, future advancements and ethical implications of gene therapy.
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SIRS SCI2 21 (Browse shelf) Available

This MARC record contains two articles.

Articles Contained in SIRS Enduring Issues 2002.

Originally Published: Betting on Designer Genes, Jan. 2001; pp. 28-36.

Originally Published: New Pairs of Genes, Jan./Feb. 2001; pp. 105-107.

BETTING ON DESIGNER GENES -- "Scientists dream of giving people new genes that will stop a disease or fix a problem. It is harder than anyone thought." (SMITHSONIAN) This article reviews the development of gene-therapy techniques and examines problems that have stymied further progress.

NEW PAIRS OF GENES -- "Although progress in gene therapy has been slow, it seems certain to be ultimately successful. The accumulated knowledge from basic research is providing multiple novel approaches to overcome problems and limitations. Progress in sequencing the human genome is providing a wealth of new material and identifying more diseases that have a genetic basis. For now the focus is on improving the vectors, the expression systems and the ability to target particular cells. The recent encouraging result with immune deficiency and haemophilia augur success. Yet as we anticipate further progress, it would be wise to ponder the deeper meanings of our ability to manipulate our genetic heritage, and what it portends for our future." (WORLD LINK) This article examines the techniques, applications, future advancements and ethical implications of gene therapy.

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